Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCL1 All Species: 24.55
Human Site: Y706 Identified Species: 41.54
UniProt: Q15111 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15111 NP_006217.3 1095 122728 Y706 I M R D E V S Y F S A N T K G
Chimpanzee Pan troglodytes XP_001169560 1095 122728 Y706 I M R D E V S Y F S A N T K G
Rhesus Macaque Macaca mulatta XP_001089483 1095 122754 Y706 I M R D E V S Y F S A N T K G
Dog Lupus familis XP_536020 1096 122535 Y707 I M R D E V S Y F S A N T K G
Cat Felis silvestris
Mouse Mus musculus Q3USB7 1096 122654 Y707 I M R D E V S Y F S A N T K G
Rat Rattus norvegicus Q62688 1096 122754 Y707 I M R D E V S Y F S A N T K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507313 1051 118878 F663 I M R E E I S F F S A N T K D
Chicken Gallus gallus Q2VRL0 637 72514 M311 C G T I E E T M L R K G R D S
Frog Xenopus laevis Q32NH8 758 87399 L432 E L R G K I L L K G K K I G R
Zebra Danio Brachydanio rerio A5D6R3 784 89362 K458 G R I L L K G K K L N G L L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13217 1095 124845 D671 F M R R A D K D F D P F A D A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_741067 1068 120024 V671 V M K D D M F V P S D R V P T
Sea Urchin Strong. purpuratus XP_001178766 684 77475 I358 C Q I V S P Q I L H I K I I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32383 869 100529 Y543 P S S F S S S Y E S A N E Q E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 98.7 96.4 N.A. 94.3 94.1 N.A. 62.9 21.7 24.7 27.9 N.A. 20 N.A. 39 35.8
Protein Similarity: 100 100 99.2 98.5 N.A. 96.6 96.6 N.A. 77.1 34.8 40.4 42.3 N.A. 40.2 N.A. 59.4 48.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 73.3 6.6 6.6 6.6 N.A. 20 N.A. 20 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 13.3 26.6 6.6 N.A. 20 N.A. 46.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 0 58 0 8 0 8 % A
% Cys: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 50 8 8 0 8 0 8 8 0 0 15 8 % D
% Glu: 8 0 0 8 58 8 0 0 8 0 0 0 8 0 8 % E
% Phe: 8 0 0 8 0 0 8 8 58 0 0 8 0 0 0 % F
% Gly: 8 8 0 8 0 0 8 0 0 8 0 15 0 8 50 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 50 0 15 8 0 15 0 8 0 0 8 0 15 8 0 % I
% Lys: 0 0 8 0 8 8 8 8 15 0 15 15 0 50 0 % K
% Leu: 0 8 0 8 8 0 8 8 15 8 0 0 8 8 0 % L
% Met: 0 65 0 0 0 8 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 58 0 0 0 % N
% Pro: 8 0 0 0 0 8 0 0 8 0 8 0 0 8 0 % P
% Gln: 0 8 0 0 0 0 8 0 0 0 0 0 0 8 0 % Q
% Arg: 0 8 65 8 0 0 0 0 0 8 0 8 8 0 8 % R
% Ser: 0 8 8 0 15 8 58 0 0 65 0 0 0 0 15 % S
% Thr: 0 0 8 0 0 0 8 0 0 0 0 0 50 0 8 % T
% Val: 8 0 0 8 0 43 0 8 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _